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SUPRAX tablets and suspensiongiven orallyare about 40to 50absorbed whether administered with or without foodhowevertime to maximal absorption is increased approximately 0.8 hours when administered with foodA single 200 mg tablet of cefixime produces an average peak serum concentration of approximately how to use viagra for best results. 2 mcg/mLrange 1 to 4 mcg/mLa single 400 mg tablet produces an average peak concentration of approximately 3.7 mcg/mLrange 1.3 to 7.7 mcg/mLThe oral suspension produces average peak concentrations approximately 25to 50higher than the tabletswhen tested in normal adult volunteersTwo hundred and 400 mg doses of oral suspension produce average peak concentrations of 3 mcg/mLrange 1 to 4.5 mcg/mLand 4.6 mcg/mLrange 1.9 to 7.7 mcg/mLrespectivelywhen tested in normal adult volunteersThe area under the time versus concentration curveAUCis greater by approximately 10to 25with the oral suspension than with the tablet after doses of 100 to 400 mgwhen tested in normal adult volunteersThis increased absorption should be taken into consideration if the oral suspension is to be substituted for the tabletBecause of the lack of bioequivalencetablets should not be substituted for oral suspension in the treatment of otitis mediasee DOSAGE AND ADMINISTRATIONCross-over studies of tablet versus suspension have not been performed in children.

SUPRAX is indicated in the treatment of adults and pediatric patients six months of age or older with pharyngitis and tonsillitis caused by susceptible isolates of Streptococcus pyogenesNotePenicillin is the usual drug of choice in the treatment of Streptococcus pyogenes infectionsSUPRAX is generally effective in the eradication of Streptococcus pyogenes from the nasopharynxhoweverdata establishing the efficacy of SUPRAX in the subsequent prevention of rheumatic fever is not available

A false-positive reaction for ketones in the urine may occur with tests using nitroprusside but not with those using nitroferricyanide.

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